Implementation of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) and Antimicrobial Stewardship Intervention at an Academic Medical Center
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164Lessons Learned from Early Implementation of Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS) with Antimicrobial Stewardship, A Pilot Study
164. Lessons Learned from Early Implementation of Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS) with Antimicrobial Stewardship, A Pilot Study Connie Park, MD; Wendy Szymczak, PhD, MT; Iona Munjal, MD; Michael Levi, ScD, (D) ABMM; Phillip Gialanella, MS; Yi Guo, PharmD; Julie E. Williamson, PharmD; Philip Chung, PharmD, MS; Rafael Ruiz, PhD, ScM; Pri...
متن کاملCost Analysis of Implementing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Plus Real-Time Antimicrobial Stewardship Intervention for Bloodstream Infections.
Studies evaluating rapid diagnostic testing plus stewardship intervention have consistently demonstrated improved clinical outcomes for patients with bloodstream infections. However, the cost of implementing new rapid diagnostic testing can be significant, and such testing usually does not generate additional revenue. There are minimal data evaluating the impact of adding matrix-assisted laser ...
متن کاملImpact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia.
BACKGROUND Integration of rapid diagnostic testing via matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) with antimicrobial stewardship team (AST) intervention has the potential for early organism identification, customization of antibiotic therapy, and improvement in patient outcomes. The objective of this study was to assess the impact of this combined approach on clinica...
متن کاملImpact of antimicrobial stewardship intervention on coagulase-negative Staphylococcus blood cultures in conjunction with rapid diagnostic testing.
Rapid diagnostic testing with matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) decreases the time to organism identification by 24 to 36 h compared to the amount of time required by conventional methods. However, there are limited data evaluating the impact of MALDI-TOF with real-time antimicrobial stewardship team (AST) review and intervention on antimicrobial prescribing...
متن کاملMALDI-ToF Mass Spectrometry: Microbiology and Physics Collide
Highlights 1. In October 2014, three DSM microbiology laboratories received MALDI-ToF instruments for identification of bacterial pathogens and will be implementing this technology in Winnipeg and Brandon over the next several months. 2. MALDI-ToF will result in decreased turnaround times for identification of pathogens, greater accuracy and lower costs of identification. 3. Combined with a pro...
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